Vitamin D Deficiency Associated Hyperparathyroidism May Be Related With Impaired Glucose Tolerance Without Any Associations With Cardiovascular Risk Factors

Introduction: Secondary hyperparathyroidism due to vitamin D deficiency (VDD) is thought play a role in glucose homeostasis. The aim of this study was determine the association parathormone and with prediabetes its different cardiovascular risk factors. Methods: This crosssectional conducted among 117 adults newly detected prediabetes. Participants were recruited consecutively from Department Endocrinology, BSMMU measure serum 25- hydroxyvitamin by high performance liquid chromatography, intact (iPTH) chemiluminescent enzyme-labeled immunometric assay; fasting insulin microparticle immunoassay oxidase method calculate homeostasis model assessment resistance (HOMA-IR). Results: Patients had significantly higher percentages VDD than those normal parathyroid status. Only impaired tolerance (IGT) status significant combined iPTH groups. Serum correlated age, HbA1C, HOMA-IR. Hyperparathyroidism predictive only IGT hypovitaminosis Conclusion: PTH may be associated glycemic dysregulation especially without any associations Bangladesh J Medicine 2022; 33: 154-160